Updates from the IMPACT Consortium and our collaborating centers.
IMPACT investigator Coco de Koning received a KWF Young Investigator Grant to study blood-based biomarkers for the early detection of acute graft-versus-host disease in children undergoing hematopoietic cell transplantation.
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IMPACT Consortium co-leader Jaap Jan Boelens was appointed the inaugural Chief Medical Officer of the International Society for Cell & Gene Therapy (ISCT), bringing his expertise in pediatric transplantation and cellular therapy to the Society's clinical leadership.
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Alexandre Troullioud Lucas completed his PhD at Utrecht University, with research helping build and expand the IMPACT Consortium's international collaboration and its approach to studying immune recovery after pediatric HCT.
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IMPACT investigators contributed to the Clinical CGT Immune Monitoring and Immunobiology Workshop at ISCT 2026, with presentations spanning immune reconstitution, thymic recovery, proteomics, and post-HCT leukemia control.
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A multicenter IMPACT Consortium analysis examined determinants of thymic recovery after pediatric allogeneic HCT across more than 400 patients, highlighting the effects of age and severe acute GVHD on immune reconstitution.
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IMPACT investigators contributed to new ISCT Stem Cell Engineering Committee guidelines outlining practical approaches for immune monitoring after hematopoietic cell transplantation and cellular therapy.
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Devin McAvoy received an ISCT Host Region Abstract Award for a multicenter analysis examining the impact of age and acute GVHD on thymic reconstitution after pediatric and young adult HCT.
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